Case Contents

Table of Contents

How to Use This Course

What Is Uranium?

Exposure Pathways

Standards, Regulations

Biological Fate

Pathogenic Changes

Physiological Effects

Clinical Assessment

More Information

Literature Cited

Printer-Friendly

Printer-Friendly

Related Documents

Interaction Profile

ToxFAQs™: Uranium

Tox Profile: Uranium

Environmental Medicine

Continuing Education

Online Registration

Patient Education

Community Education

ATSDR Resources

ATSDR en Español

Case Studies (CSEM)

Exposure Pathways

Health Assessments

Health Statements

Interaction Profiles

Interactive Learning

Managing Incidents

Medical Guidelines

Minimal Risk Levels

ToxFAQs™ CABS

Toxicological Profiles

Toxicology Curriculum

External Resources

Agency for Toxic Substances and Disease Registry
Case Studies in Environmental Medicine (CSEM)
Uranium Toxicity
Table of Contents

Course: WB 1524
CE Original Date: May 1, 2009
CE Expiration Date: May 1, 2012

Cover Page

Key Concepts

CSEM

Continuing Education

Acknowledgments

Disclaimer

How to Use This Course

Introduction

Available Versions

Instructions

Instructional Format

Learning Objectives

Initial Check

Instructions

Case Study

Initial Check Questions

Initial Check Answers

What Is Uranium?

Learning Objectives

Definition

Where Found

Milling and Radioactive Wastes

Three Types of Natural Uranium

Processing

Natural Uranium

Enriched Uranium

Depleted Uranium

Key Points

Progress Check

Where Is Uranium Found?

Learning Objectives

Introduction

The Natural Environment

DOE and Civilian Reactor Sites

Key Points

Progress Check

What Are the Routes of Exposure for Uranium?

Learning Objectives

Introduction

Inhalation

Ingestion

Skin

Key Points

Progress Check

Who Is at Risk of Exposure to Uranium?

Learning Objectives

Introduction

Past Occupational Exposures

Past Paraoccupational Exposures

Current Occupational Exposures

Direct Domestic Exposures

Background Exposures

Key Points

Progress Check

What are the Standards and Regulations for Uranium Exposure?

Learning Objectives

Introduction

Workplace Standards

Environmental Standards

Key Points

Progress Check

What Is the Biological Fate of Uranium in the Body?

Learning Objectives

Introduction

Inhalation Exposure

Ingestion Exposure

Fate of Ingested Uranium

Key Points

Progress Check

How Does Uranium Induce Pathogenic Changes?

Learning Objectives

Introduction

Mechanisms

Primary Sites Affected

Carcinogenicity

Key Points

Progress Check

What Are the Physiological Effects of Uranium Exposure?

Learning Objectives

Introduction

Nephrotoxicity in Experimental vs. Non-experimental Settings

Health Effect Differences between Children and Adults

Key Points

Progress Check

Clinical Assessment

Learning Objectives

Introduction

Exposure History

Medical History

Physical Exam

Biomarkers of Exposure and Effect

Differential Diagnosis

Key Points

Progress Check

How Should Patients Exposed to Uranium Be Treated and Managed?

Learning Objectives

Introduction

If Overexposure is Suspected or Known

Monitoring

Treatment

Instructions to Patients

Key Points

Progress Check

Sources of Additional Information

Uranium Specific

Clinical Resources

Environmental Health

Posttest

Introduction

CE Credits Offered

Disclaimer

Online Instructions

Posttest

Relevant Content

Literature Cited

Printer-Friendly

Next Section

Revised 2009-05-01.