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Chemical Mixtures Program

Program Assessment Objectives

  • Develop Interactions Profiles. Similar to the Agency toxicological profiles, these documents summarize the health effects caused by exposure to chemicals in a mixture.
  • Develop a Guidance Manual for the Assessment of Joint Toxic Action of Chemical Mixtures. A manual to assist health assessors in determining the impact of chemical mixture exposure on public health.
  • Develop Minimal Risk Level (MRLs) for chemical mixtures. Use existing methods to derive health guidance values for mixtures such as chlorinated dibenzodioxins (CDDs) and polybrominated biphenyls (PBBs).
  • Perform weight of evidence analyses for combinations of chemicals. These analyses are used to predict the influence of one chemical on the health effects of another chemical.
  • Conduct laboratory studies in collaboration with the National Institute of Environmental Health Sciences and TNO Nutrition and Food Research Institute (The Netherlands) to validate weight of evidence analyses.

Contact Us:
  • Agency for Toxic Substances and Disease Registry
    4770 Buford Hwy NE
    Atlanta, GA 30341-3717 USA
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    TTY: (888) 232-6348
    Email CDC-INFO
  • New Hours of Operation
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Agency for Toxic Substances and Disease Registry, 4770 Buford Hwy NE, Atlanta, GA 30341
Contact CDC: 800-232-4636 / TTY: 888-232-6348

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