CAS ID #: 79-01-6
Affected Organ Systems: Developmental (effects during periods when organs are developing) , Neurological (Nervous System)
Cancer Classification: EPA: Carcinogenic to humans, IARC: Carcinogenic to humans (evidence for cancer is based on kidney cancer, limited evidence for non-Hodgkin lymphoma and liver cancer, as well as, various tumors in animals). NTP: See note below.
Chemical Classification: Volatile organic compounds
Summary: Trichloroethylene (TCE) is a nonflammable, colorless liquid with a somewhat sweet odor and a sweet, burning taste. It is used mainly as a solvent to remove grease from metal parts, but it is also an ingredient in adhesives, paint removers, typewriter correction fluids, and spot removers. Trichloroethylene is not thought to occur naturally in the environment. However, it has been found in underground water sources and many surface waters as a result of the manufacture, use, and disposal of the chemical.
NOTE: In January, 2015, NTP issued a preliminary listing recommendation that trichloroethylene is known to be a human carcinogen based on sufficient evidence of carcinogenicity from humans. Trichloroethylene is currently listed in the 13th RoC (2014) as reasonably anticipated to be a human carcinogen.
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Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile.
U.S. Marine Corps Base Camp Lejeune, North Carolina was established in 1942. In 1982, the Marine Corps discovered specific volatile organic compounds (VOCs) in the drinking water provided by two of the eight water treatment plants on base.
Water from the Tarawa Terrace Treatment Plant was contaminated by PCE (perchloroethylene or tetrachloroethylene).
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Toxicological and Health Professionals
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The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure.
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- Page last reviewed: March 3, 2011
- Page last updated: March 3, 2011
- Content source: Agency for Toxic Substances and Disease Registry