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  1. No chemical contaminants were detected in ambient air of the nearest residence at levels of health concern.

  2. The levels of methyl bromide detected in the ambient air at the perimeter of GLCC are not at levels known to cause respiratory irritations. However, no ambient air monitoring around GLCC took place before 1990. The occurrence of respiratory illnesses could not be evaluated during this time because of the lack of sampling data.

  3. No human exposure is occurring to contaminants detected in on-site groundwater.

  4. The contaminants detected in off-site surface water, sediments, and soil are not expected to cause adverse health effects.

  5. No evidence exists of a correlation between blood bromide levels of nearby residents and adverse health effects.

  6. No association was found between environmental contamination from any source (including GLCC) and the MND mortality in El Dorado, Arkansas.

ATSDR selects one of five conclusion categories to summarize our findings about a site. These categories are: 1) Urgent Public Health Hazard, 2) Public Health Hazard, 3) Indeterminate Health Hazard, 4) No Apparent Public Health Hazard, and 5) No Public Health Hazard. A category is selected from site specific conditions such as the degree of public health hazard based on the presence and duration of human exposure, contaminant concentration, the nature of toxic effects associated with site related contaminants, presence of physical hazards, and community health concerns. Based on these criteria, ATSDR categorized the Great Lakes Chemical Corporation site as a No Apparent Public Health Hazard based on available off-site environmental monitoring data and the lack of human exposure to the on-site contamination.


Based upon the conclusions and information reviewed, ATSDR makes the following recommendation:

  1. Continue monitoring on-site groundwater to determine whether contamination is migrating off-site.


The actions described in this section are designed to ensure that this public health assessment identifies public health hazards and provides a plan of action to mitigate and prevent adverse health effects resulting from exposure to hazardous substances in the environment.

Actions Completed:

  1. ATSDR has completed a full site investigation that included:
  • Interviewing state health agencies, state environmental agencies, and community members

  • Monitoring environmental media

  • Evaluating exposure situations
  1. ATSDR wrote three health consultations and two exposure investigations during 1994-1996 to address health effects, environmental contamination, and exposure to GLCC emissions.

Actions Ongoing:

  1. There are no current activities ongoing at this site.

Actions Planned:

  1. ATSDR will review additional environmental data if site conditions change.

Preparer of Report:

Kimberly K. Chapman, MSEH
Environmental Health Scientist

Buck Grissom, PhD

Gregory M. Zarus, MS
Atmospheric Scientist

Reviewers of Report:

Donald Joe, PE
Section Chief

John E. Abraham, PhD
Branch Chief

Review and Approval of This Public Health Assessment for Great Lakes Chemical Corporation


Environmental Health Scientist, PRS, EICB, DHAC

Section Chief, PRS, EICB, DHAC

Branch Chief, EICB, DHAC


  1. U.S. Environmental Protection Agency. 1992. Great Lakes Chemical Corporation, El Dorado, Arkansas Case Study. ARD043195429.

  2. Eastern Research Group. May 2, 1999. Summary of environmental monitoring data collected in the vicinity of the Great Lakes Chemical Corporation "main plant" in El Dorado, Arkansas. Task Order No. 0901-05. Lexington, MA.

  3. Encor. May 11, 1993. 1993 Groundwater Quality Assessment: RCRA Part B Permit 18-H. Final Report, Volume IV. Prepared for Great Lakes Chemical Corporation. Baton Rouge, LA.

  4. ATSDR Official Record of Activity. September 21, 1999. Telephone conversation between Brent Parker of ADEQ and Kimberly Chapman ATSDR. Atlanta, GA.

  5. United States Bureau of the Census. 1990. Census of Population and Housing: Summary Tape File 1B. Department of Commerce. Washington DC.

  6. Right to Know Network. 1997. Internet Web Page:

  7. ATSDR. November 9, 1994. Great Lakes Chemical Corporation Health Consultation. Atlanta, GA.

  8. United States Environmental Protection Agency. October 22, 1997. Region III Risk-Based Concentration Table. Philadelphia, PA 19107.

  9. ATSDR. June 12, 1995. Exposure Investigation: Great Lakes Chemical Company Area, El Dorado, Arkansas. Atlanta, GA.

  10. Aquaterra, Inc. 1995. Description of Current Conditions. Report written for Great Lakes Chemical Corporation.

  11. ATSDR. February 22, 2000. Toxicological Profile for 1,2-Dichloroethane. US Department of Health and Human Services. Atlanta, GA.

  12. ATSDR. July, 1992. Toxicological Profile for 1,2-Dibromoethane. US Department of Health and Human Services. Atlanta, GA.

  13. Arkansas Department of Pollution Control and Ecology. 1991. Private Well Survey: Vicinity of Great Lakes Chemical Corporation. Report written for the Environmental Protection Agency. Little Rock, AR.

  14. ATSDR. August 1995. Toxicological Profile for Polycyclic Aromatic Hydrocarbons. US Department of Health and Human Services. Atlanta, GA.

  15. Encor. February 1993. Description of Current Conditions, RCRA Part B Permit 18-H. Final report written for Great Lakes Chemical Company. Baton Rouge, LA.

  16. Kaneda, M., N. Hatakenaka, S. Teramoto, and K. Maita. 1993. A two-generation reproduction study in rats with methyl bromide-fumigated diets. Food Chem. Toxicol. 31:533-42.

  17. Disse, M., F. Joo, H. Schulz, and J.R. Wolff. 1996. Prenatal exposure to sodium bromide affects the postnatal growth and brain development. J Hirnforsch. 37:127-34.

  18. United States Environmental Protection Agency. October 22, 1997. Region III Risk-Based Concentration Table. Philadelphia, PA 19107.

  19. ATSDR. June 12, 1995. Exposure Investigation: Great Lakes Chemical Company Area, El Dorado, Arkansas. Atlanta, GA.

  20. Tietz, N.E. (ed) 1976. Fundamentals of Clinical Chemistry.

  21. ATSDR. November 1996. Exposure Investigation: Great Lakes Chemical Company Area, El Dorado, Arkansas. Atlanta, GA.

  22. ATSDR. October 17, 1994. Great Lakes Chemical Corporation Health Consultation.

  23. Kurtzke, John F. 1991. Risk Factors in Amyotrophic Lateral Sclerosis, p. 245-270 in Advances in Neurology, Vol. 56: Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases. Lewis P. Rowland, ed., Raven Press.

  24. Chancellor, A.M., and C.P. Warlow. 1992. Adult Onset Motor Neuron Disease: Worldwide Mortality, Incidence, and Distribution Since 1950. Journal of Neurology, Neurosurgery, and Psychiatry. Vol. 55, p 1106-1115.

  25. Swash, M. And M.S. Schartz. 1992. What Do We Really Know About Amyotrophic Lateral Sclerosis? Journal of Neurological Sciences, Vol. 113, p. 4-16.

  26. Williams, D.B. and A.J. Windbank. 1991. Subject Review: Motor Neuron Disease (Amyotrophic Lateral Sclerosis). Mayo Clinic Proceedings, Vol. 66. P. 54-82.

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