Ethylene Oxide

Toxicological Profile
For Public Health

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile characterizes the toxicologic and adverse health effects of ethylene oxide.

Details

Title: Toxicological Profile for Ethylene Oxide

Subject of Planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on these hazardous substances supports public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): 1/22/2020; 12/26/2021 (inhalation MRL update)

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public Comment (how and when): A draft of this profile was made available for public comment in 2020.

Peer Reviewers Provided with Public Comments before the Review: No

Number of Reviewers: 7

Primary Disciplines or Expertise: Toxicology, Toxicological pathology, Epidemiology, Environmental Health, Chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials

MD

PhD

Current Position Title

Professor

Organizational Affiliation(s)

Veterinary Integrative Biosciences
College of Vet Medicine & Biomedical Sciences
Texas A&M University

Areas of Expertise, Discipline, Relevant Experiences

  • Pharmacology
  • Toxicology
  • Risk assessment methods for carcinogens
  • Hepatic toxicity
  • DNA damage and repair
  • Mutagenesis
  • Carcinogenesis
  • Mechanisms of action of environmental toxicants and the genetic determinants of the susceptibility to toxicant-induced injury

Recommended by Scientific/Professional Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Professor

Organizational Affiliation(s)

Professor, Department of Environmental Health
Professor, Department of Epidemiology
Rollins School of Public Health
Emory University

Areas of Expertise, Discipline, Relevant Experiences

  • Statistical modeling
  • Environmental health
  • Epidemiology
  • Pesticides in relation to neurodegenerative diseases
  • Adult lead exposure and cancer
  • PFOA and a variety of diseases

Recommended by Scientific/Professional Society or General Public

No

Academic and Professional Credentials

Current Position Title

Group Lead, Ambient Aire Monitor Group

Organizational Affiliation(s)

Office of Air Quality Planning & Standards
U.S. Environmental Protection Agency

Areas of Expertise, Discipline, Relevant Experiences

  • EPA expert on EPA national ambient air monitoring networks for multiple pollutants
  • Particular expertise on ethylene oxide air levels
  • Eight publications from 2005-2019, cited by 428 other papers

Weinstock also has expertise crucial for review of 5.3.1 Potential for Human Exposure: Releases to The Environment: Air (air monitoring measurements & methods) to ensure that information is complete and accurate

Recommended by Scientific/Professional Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Professor Emeritus

Organizational Affiliation(s)

Environmental Health Sciences,
Lawrence Berkeley National Laboratory,
UC Berkeley School of Public Health

Areas of Expertise, Discipline, Relevant Experiences

  • Risk assessment
  • Model uncertainty and reliability in exposure/risk assessment
  • Environmental and occupational radioactivity
  • Mass transfer at environmental and human/environment boundaries

Recommended by Scientific/Professional Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Director, Analytical Chemistry & Pharmaceutics

Organizational Affiliation(s)

RTI International
Research Triangle Park
North Carolina, USA

Areas of Expertise, Discipline, Relevant Experiences

  • Biomarkers
  • Exposure assessment
  • Pharmacokinetics
  • Nanotoxicology
  • Biochemistry

Recommended by Scientific/Professional Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Associate Professor

Organizational Affiliation(s)

Pathobiology and Diagnostic Investigation
College of Veterinary Medicine;
Michigan State University

Areas of Expertise, Discipline, Relevant Experiences

  • Pathophysiology and pharmacology
  • Toxicology
  • Mechanisms of airway injury and systemic responses induced by inhalation exposures to pathogens, toxicants, and environmental pollutants
  • Role of diet and metabolic susceptibility in adverse cardiopulmonary responses to air pollutant exposure
  • Nanomaterials

Recommended by Scientific/Professional Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Professor

Organizational Affiliation(s)

University of Cincinnati

Areas of Expertise, Discipline, Relevant Experiences

Pathology and toxicology

Recommended by Scientific/Professional Society or General Public

No
Content Source
Agency for Toxic Substances and Disease Registry
About This Page
Published: November 12, 2024
Updated: August 2, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 27, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.