Mirex and Chlordecone

Toxicological Profile
For Public Health

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile characterizes the toxicologic and adverse health effects of mirex and chlordecone.

Details

Title: Toxicological Profile for Mirex and Chlordecone.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Type of Dissemination: ISI

Timing of Review (including deferrals): April 2018

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile was made available for public comment June 2019.

Peer Reviewers Provided with Public Comments before the Review: No

Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials

PhD

Current Position Title

Senior Scientist Emeritus

Organizational Affiliation(s)

Lovelace Respiratory Research Institute

Areas of Expertise, Discipline, Relevant Experiences

Expertise / Discipline:

  • Toxicology
  • Biochemistry
  • Chemistry

Experience:

  • Served on Special Study Sections of the National Institutes of Health and the Health Effects Institute to review grant proposals in the area of lung biochemistry
  • Developed in vivo screening tests for pulmonary toxicants based on analysis of bronchoalveolar washings for biomarkers of lung injury and repair
  • Research on the mechanisms by which pulmonary inflammation leads to repair or to chronic disease (fibrosis, emphysema)
  • Research on the pharmacokinetics of inhaled xenobiotics (particularly vapors) and chemical-specific biomarkers of chemical exposure

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PharmD

Current Position Title

Professor

Organizational Affiliation(s)

Department of Environmental and Occupational, Health Sciences, School of Public Health, University of Washington

Areas of Expertise, Discipline, Relevant Experiences

Expertise / Discipline:

Experimental pharmacology and neurotoxicology


Experience:

Director, Neurotoxicology Research Core, NIEHS Center in Ecogenetics and Environmental Health, University of Washington


University of Washington Core faculty in:

  • Interdisciplinary Molecular and Cellular Biology Program
  • Environmental and Occupational Epidemiology Training Program
  • Environmental Pathology/Toxicology Training Program (Director of Neurotoxicology and Developmental Toxicology Core)

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

MD

PhD

Current Position Title

Research Director

Organizational Affiliation(s)

Inserm U1085 – IRSET, Research Institute of Occupational and Environmental Health

Areas of Expertise, Discipline, Relevant Experiences

Expertise / Discipline:

  • Epidemiology
  • Reproduction
  • Fertility
  • Prostate cancer
  • Hormone dependent cancers
  • Prenatal and post-natal development
  • Endocrine disruptors

Experience:

Head of the Guadeloupe Site of Inserm U1085 – IRSET. Head of the Team: “Exposure Assessment And Epidemiological Research on Environment, Reproduction, and Development (3ERD),” Inserm U1085 – IRSET, Rennes, France.

Recommended by Scientific/Professional
Society or General Public

No
Content Source
Agency for Toxic Substances and Disease Registry
About This Page
Published: November 12, 2024
Updated: August 28, 2026

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 28, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.