Tetrachloroethylene (PERC)

Toxicological Profile
For Public Health

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile characterizes the toxicologic and adverse health effects of Tetrachloroethylene (PERC).

Details

Title: Toxicological Profile for Tetrachloroethylene (PERC)

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2013

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile was made available for public comment in 2014.

Peer Reviewers Provided with Public Comments before the Review: No

Number of Reviewers: 6

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials

PhD

Current Position Title

Professor

Organizational Affiliation(s)

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY

Areas of Expertise, Discipline, Relevant Experiences

  • Protection of children from immune dysfunction-based chronic diseases
  • Developmental immunotoxicity of environmental chemicals and drugs and the adverse outcomes
  • Patterns of interlinked chronic diseases
  • Immunotoxicity testing to protect against chronic diseases
  • Intervention strategies

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Professor

Organizational Affiliation(s)

Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY

Areas of Expertise, Discipline, Relevant Experiences

  • Protection of children from immune dysfunction-based chronic diseases
  • Developmental immunotoxicity of environmental chemicals and drugs and the adverse outcomes
  • Patterns of interlinked chronic diseases
  • Immunotoxicity testing to protect against chronic diseases
  • Intervention strategies

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Research Scientist

Organizational Affiliation(s)

Department of Environmental Sciences & Engineering, Gillings School of Global Public Health, University of North Carolina, Chapel Hill

Areas of Expertise, Discipline, Relevant Experiences

Spatiotemporal variability of tetrachloroethylene in residential indoor air due to vapor intrusion


Environmental epidemiology

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

MPH

Current Position Title

Scientist

Organizational Affiliation(s)

IARC Monographs Programme
International Agency for Research on Cancer
World Health Organization
Lyon, France

Areas of Expertise, Discipline, Relevant Experiences

Cancer hazard identification
Environmental and occupational cancer hazards

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Scientist Emeritus

Organizational Affiliation(s)

National Cancer Institute
Division of Cancer Epidemiology & Genetics,
Occupational and Environmental Epidemiology Branch
Rockville, Maryland

Areas of Expertise, Discipline, Relevant Experiences

  • Cancer
  • Environmental epidemiology
  • Occupational and environmental causes of cancer

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

DABT

Current Position Title

Scientist

Organizational Affiliation(s)

Monographs Section
International Agency for Research on Cancer
World Health Organization
Lyon, France

Areas of Expertise, Discipline, Relevant Experiences

  • Cancer
  • Mechanisms of carcinogenicity
  • Risk assessment
  • Cancer prevention

Recommended by Scientific/Professional
Society or General Public

No
Content Source
Agency for Toxic Substances and Disease Registry
About This Page
Published: November 12, 2024
Updated: August 6, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 28, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.