Toluene Diisocyanate

Toxicological Profile
For Public Health

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile characterizes the toxicologic and adverse health effects of toluene diisocyanate.

Details

Title: Toxicological Profile for Toluene Diisocyanate

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2014

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile was made available for public comment in 2015.

Peer Reviewers Provided with Public Comments before the Review: No

Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials

PhD

Current Position Title

Principal Consultant

Organizational Affiliation(s)

Systox, Ltd.
84 Hazelwood Rd
Wilmslow, Cheshire, SK92QA
United Kingdom

Areas of Expertise, Discipline, Relevant Experiences

Areas of Interest:

  • Mammalian and environmental toxicology expertise
  • Regulatory compliance and conformity declarations
  • The production of global product safety documentation
Experience:
  • Chairman of the US Methacrylate Producers Association (MPA), Science Committee and the US Cyanide Council Toxicology Committee, the US Cyanide Counsel
  • Member of the US Acylonitrile Association
  • Sits on several European, US and UK, National regulatory panels and workgroups
  • A member of the European Centre for Ecotoxicology and Toxicology of Chemicals (ECETOC) Scientific Committee

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

DABT

Current Position Title

Senior Toxicologist

Organizational Affiliation(s)

Gradient Corporation
20 University Rd.
Cambridge, Massachusetts

Areas of Expertise, Discipline, Relevant Experiences

  • Toxicology
  • Exposure assessment
  • Cell and molecular biology
  • Human genetics
  • Environmental toxicology

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

DABT

Current Position Title

Research Associate

Organizational Affiliation(s)

Global Safety Assessment and Regulatory Affairs


S.C. Johnson & Son, Inc., Racine, WI

Areas of Expertise, Discipline, Relevant Experiences

  • Environmental assessment
  • Environmental fate
  • Ecotoxicology
  • Human and environmental safety assessment of consumer products, including laundry products, insect control products, cleaners, candles, industrial chemicals, radionuclides, insecticides, herbicides, and fungicides, etc.

Recommended by Scientific/Professional
Society or General Public

No
Content Source
Agency for Toxic Substances and Disease Registry
About This Page
Published: November 12, 2024
Updated: August 6, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 28, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.