Trichloroethylene (TCE)

Toxicological Profile
For Public Health

At a glance

NCEH/ATSDR makes peer review information available to demonstrate efforts to utilize transparent and independent peer review, appropriate research methods, and the highest level of data quality. This ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects of trichloroethylene (TCE).

Details

Title: Toxicological Profile for Trichloroethylene (TCE)

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data. Data on hazardous substances most commonly found at hazardous waste sites support public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2013

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for Public Comment (how and when): A draft of this profile was made available for public comment in 2014.

Peer Reviewers Provided with Public Comments before the Review: No

Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

Reviewers

Academic and Professional Credentials

PhD

DABT

Current Position Title

Research Scientist

Organizational Affiliation(s)

Office of Science, New Jersey Department of Environmental Protection, Trenton, NJ

Areas of Expertise, Discipline, Relevant Experiences

Areas of expertise:

Human health risk assessment and toxicology research on health effects of environmental contaminants


Experience:
Dr. Post currently serves on the EPA Science Advisory Board’s Exposure and Human Health Committee. She has served on the EPA SAB Trichloroethylene Review Panel. She is a member of the NJ Drinking Water Quality Institute, a legislatively mandated advisory body to NJDEP.


Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

PhD

Current Position Title

Professor

Organizational Affiliation(s)

Department of Pharmaceutical and Biomedical Sciences, College of Pharmacy and Interdisciplinary Toxicology Program, University of Georgia, Athens, Georgia

Areas of Expertise, Discipline, Relevant Experiences

  • Basic toxicology and pharmacokinetic questions that impact assessments of risks of chemicals to human health
  • Volatile organic chemicals (VOCs) and pesticides
  • Low environmental exposures and cancer risk to humans
  • Drug-chemical interactions
  • Physiologically-based pharmacokinetic models, pyrethroid pesticides and children’s health

Recommended by Scientific/Professional
Society or General Public

No

Academic and Professional Credentials

MD

PhD

Current Position Title

Professor Emeritus

Organizational Affiliation(s)

Leibniz Research Centre for Working Environment and Human Factors, Systems toxicology group, Dortmund, Germany

Areas of Expertise, Discipline, Relevant Experiences

  • Toxicology
  • Risk assessment
  • Genotoxic carcinogens
  • Occupational standard settings

Recommended by Scientific/Professional
Society or General Public

No
Content Source
Agency for Toxic Substances and Disease Registry
About This Page
Published: November 12, 2024
Updated: August 7, 2024

This page was last updated on this date. Updates may include minor edits, image changes, or other modifications to page content.

Reviewed: August 28, 2026

The information on this page was last reviewed by subject matter experts to ensure accuracy.