Review Of ATSDR Spring Valley Exposure Investigations

Slide 1
Review Of ATSDRS
pring Valley Exposure Investigations
Slide 2
Susan W. Metcalf, MD.
Agency For Toxic Substances And Disease Registry
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Exposure Investigations
Exposure Investigations
Date Participants
AU Child Development Center Feb 2001 28 children
4 adults
Spring Valley I March 2002 23 adults
9 children
Spring Valley II July-Nov 2002 34 adults
6 children
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Child Development Center
  • Soil arsenic levels
    • 57 ppm average
    • 498 ppm highest hit
  • Children immediately relocated
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Results Of Hair Analysis
  • 24 samples: no arsenic detected
  • 8 samples: 0 .10ppm to 0 .14 ppm arsenic
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Background Hair Arsenic Levels
  • Textbooks: < 1 ppm
  • National Research Council 0.2 ppm
  • NCEH: 95th percentile: 0.28 ppm
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Spring Valley I
  • 20 homes with the highest composite samples
    • 62-202 ppm
  • Arsenic analyzed
    • Hair
    • Urine
    • House dust
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Spring Valley I Results
  • Hair samples
    • 6 non-detects
    • 19 (.07-.73 ppm)
  • House dust samples< -13 homes
    • 0-63 ppm
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Spring Valley I Results
  • Total urine arsenic
    • Range 0-210 µg/L
  • Speciated urine arsenic
    • 10,12,15 µg/L
  • BEI : 35 µg/L
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Spring Valley I Conclusions
  • Urine and hair arsenic levels are consistent with background exposure
  • These levels would not be expected to be associated with health problems
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Spring Valley II: Eligibility
  • Participation in previous EI
  • Living on or adjacent to properties as they were being remediated
  • Single elevated level of arsenic on property
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Spring Valley II
  • Total urine arsenic
    • Range 0-76 µg/L
  • Speciated urine arsenic
    • 10, 14, 29 µg/L
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Spring Valley II Conclusions
  • Overall, there was no significant arsenic exposure in the population
  • 3 individuals had measurable levels of inorganic arsenic that would not be expected to cause health problems
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Spring Valley I & II
  • 19 participants
    • Urinary arsenic measured in both investigations
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Spring Valley I & II
Speciated Arsenic
  • 17/19 participants
    • Speciated arsenic < 10 µg/L in both investigations
  • 2 individuals
    • Speciated arsenic >10 µg/L in at least one investigation
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Individual 1
Individual 1
Total As (µg/L) Inorganic As (µg/L)
EI I 94 15
EI 2 Non Detect
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Individual 2
Individual 2
Total As (µg/L) Inorganic As (µg/L)
EI I 26 12
EI 2 34
58
Non Detect
29 (13.4 µg/g creatinine)
Slide 18
Conclusions
  • All the arsenic levels found in our testing are below those associated with health problems
Page last reviewed: September 22, 2015