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Toxicological Profiles


Information About Contaminants Found at Hazardous Waste Sites

Substance Index for ToxProfiles

Finalized toxicological profiles by chemical with NTIS order number. Updates are in bold.
* denotes tox profiles funded by the Department of Defense.

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  • Lead (Updated) (PB2008-100007)























  • Xylenes (Updated) (PB2008-100008)



  • Zinc (Updated) (PB2006-100008)

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By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.

Toxicological profiles are developed in two stages:

(1) DRAFTS: The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90 day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology and Human Health Sciences.

(2) FINALS: After the 90 day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles.

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NTIS address

NTIS distributes finalized toxicological profiles for a fee. For more information, contact

National Technical Information Service
5285 Port Royal Road
Springfield, Virginia 22161
1-800-553 6847 or 703-605-6000
Web site:

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Toxicological profiles "Draft for Public Comment" - CERCLA Set 24

Toxicological profiles (under development) CERCLA Set 25

The public comment period has ended and the profiles will be revised based on relevant public comments.

Toxicological profiles (under development) CERCLA Set 26

The public comment period ends on March 15, 2015.

*Glutaraldehyde is on a modified schedule and still under development.

Toxicological profiles (under development) CERCLA Set 27

Toxicological profiles (under development) CERCLA Set 28

  • Antimony (Update)
  • 2,4-D
  • Glyphosate
  • Silica

Department of Defense (under development) – DoD5

Department of Defense (under development) – DoD6

  • 1-Bromopropane

List updated on December 12, 2014

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Federal Register Notices:

Profile Development:

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Additional Resources:

  • Public Health Statements (PHS) - The PHS are a series of summaries about hazardous substances taken from Chapter One of their respective ATSDR Toxicological Profiles.
  • ATSDR ToxFAQsTM - The ToxFAQsTM are a series of 2-page fact sheets about hazardous substances
  • ATSDR ToxGuidesTM - The ATSDR ToxGuidesTM are quick reference guides providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects.

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Contact Us:
  • Agency for Toxic Substances and Disease Registry
    4770 Buford Hwy NE
    Atlanta, GA 30341
  • 800-CDC-INFO
    TTY: (888) 232-6348
  • New Hours of Operation
    8am-8pm ET/Monday-Friday
    Closed Holidays
    Contact CDC-INFO The U.S. Government's Official Web PortalDepartment of Health and Human Services
Agency for Toxic Substances and Disease Registry, 4770 Buford Hwy NE, Atlanta, GA 30341
Contact CDC: 800-232-4636 / TTY: 888-232-6348

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