How to Use This Course

Course: WB 4342
CE Original Date: March 20, 2020
CE Renewal Date: March 20, 2022
CE Expiration Date: March 20, 2024
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Case Studies in Environmental Medicine’s goal is to increase the primary care provider’s knowledge of hazardous substances in the environment and to help in evaluation and treating of potentially exposed patients. This case study focuses on ethylene glycol and propylene glycol toxicity.


Two versions of the Ethylene Glycol/Propylene Glycol Toxicity CSEM are available.

  • The HTML version (To be added after clearance during Web production) provides content through the Internet.
  • The downloadable PDF version (To be added after clearance during web production) provides content in an electronic, printable format, especially for those who might lack adequate Internet service.
  • The HTML version offers interactive exercises and prescriptive feedback to the user.

Follow these steps to make the most effective use of this course:

  • Take the Initial Check to assess your current knowledge about ethylene glycol and propylene glycol toxicity.
  • Read the title, learning objectives, text, and key points in each section.
  • Complete the progress check exercises at the end of each section and check your answers.
  • Complete and submit your assessment and posttest response online if you want continuing education credit. You can print continuing education certificates immediately after course completion.
Instructional Format

This course is designed to help you learn efficiently. Topics are clearly labeled; you can skip sections or quickly scan sections with which you are already familiar. This labeling also allows you to use this training material as a handy reference. To help you identify and absorb important content quickly, we’ve structured each section as follows:

Instructional Format
Section Element Purpose
Title Serves as a “focus question” you should be able to answer after completing the section
Learning Objectives Describes specific content addressed in each section and focuses your attention on important points
Text Provides the information you need to answer the focus question(s) and achieve the learning objectives
Key Points Highlights important issues and helps you review
Progress Check exercises Enables you to test yourself to determine whether you have mastered the learning objectives
Progress Check answers Provides feedback to ensure you understand the content and can locate information in the text
Learning Objectives

After completing the Ethylene Glycol and Propylene Glycol CSEM, you will be able to accomplish the following:

Learning Objectives
Content Area Learning Objectives
What Is Ethylene Glycol?
  • Describe the properties of ethylene glycol
Where Is Ethylene Glycol Found?
  • Identify sources of ethylene glycol exposure
What Are Routes of Exposure to Ethylene Glycol?
  • Identify the most common route of exposure to ethylene glycol that results in toxicity in the general U.S. population
Who Is at Risk of Exposure to Ethylene Glycol?
  • Identify who is at risk of exposure to ethylene glycol
What Are U.S. Regulations and Guidelines for Ethylene Glycol Exposure?
  • Describe current U.S. regulations and guidelines for ethylene glycol exposure
What Is the Biologic Fate of Ethylene Glycol?
  • Explain the major pathway of ethylene glycol metabolism in the body
What Are the Toxicological Effects of Ethylene Glycol Poisoning?
  • Describe the toxicological effects of ethylene glycol poisoning.
Clinical Assessment – History and Physical Exam
  • Describe what is included in the initial history and physical examination of patients potentially exposed to ethylene glycol
  • Describe how the clinical presentation changes over time
Clinical Assessment – Laboratory Tests
  • Identify the abnormal laboratory findings associated with ethylene glycol poisoning
  • List three measurements that can assist with diagnosis of ethylene glycol poisoning
How Should Patients Exposed to Ethylene Glycol Be Treated and Managed?
  • Describe treatment strategies for managing ethylene glycol poisoning cases
What Is Propylene Glycol?
  • Describe the uses of propylene glycol
  • Explain the potential risk of propylene glycol toxicity
What Instructions Should You Give to Patients Regarding Ethylene Glycol/Propylene Glycol Exposure?
  • Describe self-care and clinical follow-up instructions for patients exposed to ethylene glycol or propylene glycol