Example Cancer Information in PHAST for 1,2,3-Trichloropropane
This is a screenshot of a table from PHAST’s CVs and Health Guidelines Module for 1,2,3-trichloropropane. It shows the Quantitative Estimates of Carcinogenic Risk that only include the Oral Cancer Slope Factor of 30 (mg/kg/day)⁻¹. The agency, cancer class*, description, and year are shown for cancer classifications. For EPA, this includes cancer class LC, described as likely to be carcinogenic to humans, and in the year 2009. For NTP, this includes cancer class 2, described as reasonably anticipated to be a carcinogen, and in the year 2014. For IARC, this includes cancer class 2A, described as probably carcinogenic to humans (limited human evidence; sufficient evidence in animals), and in the year 1995. For NIOSH, this includes cancer class OC, described as occupational carcinogen, and no year is listed.
There is a footnote that says: *Some cancer class abbreviations were created by ATSDR and are listed here for ease of use only, and do not represent official agency classification. See Cancer Classification Systems for a summary.
Under the table in PHAST, there are these two statements:
Is contaminant classified as a mutagen? Yes
Are ADAFs applied in PHAST? Yes