Toxicological Profile for 3,3’-Dichlorobenzidine
Title: Toxicological Profile for 3,3’-Dichlorobenzidine (DCBZ)
Subject of Planned Report: The ATSDR toxicological profile succinctly reviews the toxicologic and epidemiologic literature to identify adverse health effects for the substance being described. It also summarizes environmental fate and transport mechanisms and potential for human exposure.
Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.
Type of Dissemination: ISI
Timing of Review (including deferrals): 1/13/2020
Type of Review (panel, individual or alternative procedure): Individual
Opportunities for the Public to Comment (how and when): A draft of this profile will be made available for public comment at the end of 2020 or beginning of 2021.
Peer Reviewers Provided with Public Comments before the Review: No
Anticipated Number of Reviewers: 3
Primary Disciplines or Expertise: Exposure assessment, toxicology, environmental and/or occupational health, organic chemistry, textiles engineering/chemistry
Reviewers Selected by (agency or designated outside organization): CDC/ATSDR
Public Nominations Requested for Reviewers: No
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Professor |
| Organizational Affiliation(s) | Polymer and Color Chemistry Textile Engineering, Chemistry and Science North Carolina State University |
| Areas of Expertise, Discipline, Relevant Experiences |
Organic dyes and pigments; textile chemistry including pigments, dyes, and amines as related directly to the profile substances. |
| Recommended by Scientific/Professional Society or General Public |
No |
| Academic and Professional Credentials | PhD |
|---|---|
| Current Position Title | Professor, Emeritus |
| Organizational Affiliation(s) | Department of Pharmaceutical and Biomedical Sciences College of Pharmacy, University of Georgia Athens, Georgia |
| Areas of Expertise, Discipline, Relevant Experiences | Basic toxicology and pharmacokinetic questions that impact assessments of risks of chemicals to human health; volatile organic chemicals (VOCs) and pesticides: low dose environmental exposures and cancer risk to humans; drug-chemical interactions; physiologically-based pharmacokinetic models, pyrethroid pesticides, and children’s health.
Experience: Dr. Bruckner is an environmental toxicologist whose research areas include development of in vitro testing systems for hepatorenal toxins, comparison of the relative pharmacokinetics and toxicity of inhaled and ingested organics, and investigation of the toxicity of halogenated hydrocarbons. |
| Recommended by Scientific/Professional Society or General Public |
No |
| Academic and Professional Credentials | MD Board Certified: American Board of Internal Medicine American Board of Preventive Medicine Occupational and Environmental Medicine |
|---|---|
| Current Position Title | Distinguished Professor Chief, Division of Occupational and Environmental Medicine Clinician at MSU Medicine Specialty Center, Occupational Medicine Clinic Faculty, Institute for Integrative Toxicology |
| Organizational Affiliation(s) | Michigan State University |
| Areas of Expertise, Discipline, Relevant Experiences | Extensive publications regarding chemical exposures. Decades of clinical experience. Collaboration with state health department on occupational diseases and injuries. |
| Recommended by Scientific/Professional Society or General Public |
No |
Additional elements to be added to the public posting as they become available:
CDC/ATSDR’s Response to Reviewers’ Comments: (under clearance)
The ISI/HISA Dissemination Itself: (to be released soon)