Toxicological Profile for Dinitrophenols

Title: Toxicological Profile for Dinitrophenols

Subject of Planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): May 2018

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile was made available for public comment June 2019

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. Martin D. Brand
1. Brand, Martin D.
Academic and Professional Credentials PhD
Current Position Title Professor
Organizational Affiliation(s) Buck Institute for Research on Aging
Areas of Expertise, Discipline, Relevant Experiences Expertise / Discipline: metabolism, physiology, reactive oxygen species, oxidative stress, energy metabolism, mitochondria, free radical biology
Experience: Martin Brand is an authority on mitochondria, the energy-converting unit of cells and their influence on aging and disease. After receiving his PhD in Biochemistry at the University of Bristol in the UK, he was a postdoctoral fellow at Johns Hopkins University in Baltimore, Maryland, a faculty member for over 20 years at the University of Cambridge and then a group leader at the Medical Research Council. Brand has published more than 250 peer-reviewed studies, including Nature, The Proceedings of the National Academy of Sciences, Cell Metabolism, Diabetes, Aging Cell and The Journal of Biological Chemistry
Recommended by Scientific/Professional Society or General Public No
2. David Janz
2. Janz, David
Academic and Professional Credentials MSc, PhD
Current Position Title Professor of Veterinary Biomedical Sciences and Associate Director (Academic), Toxicology Centre
Organizational Affiliation(s) Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Canada
Areas of Expertise, Discipline, Relevant Experiences Expertise / Discipline: toxicology, industrial pollutants, biochemistry, veterinary pharmacology
Experience: Development of techniques to determine long term stress in wildlife; Endogenous and exogenous factors influencing gonadal development in fish; Aquatic ecotoxicology of selenium in native fish species; Noninvasive approaches to evaluate effects of environmental stressors.
Recommended by Scientific/Professional Society or General Public No
3. David M. Wood
3. Wood, David M
Academic and Professional Credentials MD, FRCP, FACMT, FBPhS
Current Position Title physician and clinical toxicologist
Organizational Affiliation(s) Medical Toxicology Office, Guy’s and St Thomas’ NHS Foundation Trust (London, United Kingdom)
Areas of Expertise, Discipline, Relevant Experiences Expertise / Discipline: clinical toxicology, pharmacology
Experience: Fellow of the British Pharmacological Society (BPS); expertise in research of drugs and novel psychoactive substances and expert adviser to the BPS, the UK Advisory Council on the Misuse of Drugs and the European Monitoring Centre for Drugs and Drug Addiction.
Recommended by Scientific/Professional Society or General Public No
Page last reviewed: July 16, 2019