Toxicological Profile for Tribufos

Title: Toxicological Profile for Tribufos

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): November 2016

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile will be made available for public comment in 2017

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. Edna Pereira
1. Edna Pereira
Academic and Professional Credentials PhD, MSc
Current Position Title Associate Professor
Organizational Affiliation(s) Primary Appointment: Epidemiology & Public Health
Secondary Appointments: Pharmacology
University of Maryland School of Medicine
Areas of Expertise, Discipline, Relevant Experiences Molecular, cellular, and system pharmacology and toxicology; conducted numerous studies in the areas of nicotinic allosteric potentiating ligands, neuroprotective actions of galantamine, modulation of synaptic transmission in the brain, neurotoxic effects of nerve agents and organophosphorus pesticides in the mature and the developing mammalian brain.
Recommended by Scientific/Professional
Society or General Public
2. Michael Eddleston
2. Michael Eddleston
Academic and Professional Credentials MD, PhD
Current Position Title Professor of Clinical Toxicology and Lister Research Prize Fellow in the Pharmacology, Toxicology and Therapeutics Unit of the University/BHF Centre for Cardiovascular Science; Director and Consultant Physician at the National Poisons Information Service
Organizational Affiliation(s) Department of Pharmacology
Toxicology, and Therapeutics
University/BHF Centre for Cardiovascular Science
University of Edinburgh
Edinburgh , UK
Areas of Expertise, Discipline, Relevant Experiences Toxicology and pharmacology, pesticide and novel antidote treatment of other forms of poisoning (such as from cyanide, alcohol, and contrast media)
Recommended by Scientific/Professional
Society or General Public
3. Richard A. Fenske
3. Richard A. Fenske
Academic and Professional Credentials PhD, MPH
Current Position Title Associate Chair, and Professor
Organizational Affiliation(s) Environmental and Occupational Health Sciences
University of Washington
Box: 357234
1959 NE Pacific Street
Areas of Expertise, Discipline, Relevant Experiences The evaluation of environmental health risks in special populations, such as children, farm workers, and farm producers. Specialty areas include health risks of pesticide exposures, development of new exposure assessment methods, and investigation of the role of skin exposure for workers and children. Dr. Fenske received the 2006 NIOSH Director’s Award for Excellence in Research and the 2007 Jerome Wesolowski Award for Outstanding Contributions to the Field of Exposure Science from the International Society of Exposure Science He currently serves as a member of National Academy of Sciences/Institute of Medicine Roundtable on Environmental Health Sciences, Research, and Medicine. In 2008-2009 Dr. Fenske was Chair of the Institute of Medicine’s Committee to Review the Health Effects of Vietnam Veterans of Exposure to Herbicides (Seventh Biennial Update), and served from 2006-2009 as a member of the Environmental Protection Agency’s Human Studies Review Board.
Recommended by Scientific/Professional
Society or General Public

Charge to Peer Reviewers

Peer Reviewers’ Comments and CDC/ATSDR’s Response to Peer Reviewers’ Comments: Tribufos pdf icon[PDF – 1 MB]

Additional elements to be added to the public posting as they become available
Technically it is titled S,S,S-Tributyl Phosphorotrithioate (Tribufos)
It is still under development

The ISI/HISA Dissemination Itself

Page last reviewed: August 13, 2018