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Toxicological Profile for 2-Hexanone

Title: Toxicological Profile for 2-Hexanone

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances most commonly found at hazardous waste sites and in support of public health assessments at these sites.

Type of Dissemination: ISI

Timing of Review (including deferrals): September 2016

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile will be made available for public comment in 2017

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, environmental health, chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. LoPachin, Richard M.

Academic and Professional Credentials PhD
Current Position Title Professor of Anesthesiology
Director of Research
Organizational Affiliation(s) Albert Einstein College of Medicine
Montefiore Medical Center
Bronx, NY
Areas of Expertise, Discipline, Relevant Experiences Environmental toxicant exposure and endogenous disease processes; role of unsaturated aldehyde electrophiles in Alzheimer’s disease and other neurodegenerative conditions; neurotoxicity and neurodegeneration.
Recommended by Scientific/Professional Society or General Public No

2. Aschner, Michael

Academic and Professional Credentials  

PhD

Current Position Title Professor; Harold & Muriel Block Chair in Molecular Pharmacology;
Director, Einstein Center of Toxicology
Organizational Affiliation(s) Department of Molecular Pharmacology
Albert Einstein College of Medicine
Bronx, NY
Areas of Expertise, Discipline, Relevant Experiences Interaction between genetics and the environment in triggering disease both during central nervous system development and senescence; metal uptake across the blood-brain barrier and distribution in the brain, cellular and molecular mechanisms of neurotoxicity; mechanisms of transport and neurodegeneration in various experimental models
Recommended by Scientific/Professional Society or General Public No

3. Blando, James

Academic and Professional Credentials PhD
Current Position Title Associate Professor
Organizational Affiliation(s) Community & Environmental Health
Old Dominion University
Areas of Expertise, Discipline, Relevant Experiences Industrial hygiene, air pollution, environmental and occupational health and epidemiology
Recommended by Scientific/Professional Society or General Public No

Charge to Peer Reviewers: DTEM Charge to Peer Reviewers DTEM peer review policy _2_ [PDF – 165K]
Peer Reviewers’ Comments and CDC/ATSDR’s Response to Peer Reviewers’ Comments: 2-Hexanone [PDF – 320 KB]
Additional elements to be added to the public posting as they become available
The ISI/HISA Dissemination Itself

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