Toxicological Profile for Ethylene Oxide

Title: Toxicological Profile for Ethylene Oxide

Subject of Planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances to support of public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): 11/20/2019

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): A draft of this profile was made available for public comment in 2020.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 6

Primary Disciplines or Expertise: Toxicology, Toxicological pathology, Epidemiology, Environmental Health, Chemistry

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. Ivan Rusyn
1. Ivan Rusyn
Academic and Professional Credentials MD, PhD
Current Position Title Professor
Organizational Affiliation(s) Veterinary Integrative Biosciences
College of Vet Medicine & Biomedical Sciences
Texas A&M University
Areas of Expertise, Discipline, Relevant Experiences Pharmacology; Toxicology; Risk assessment methods for carcinogens; Hepatic toxicity; DNA damage and repair; Mutagenesis; Carcinogenesis; Mechanisms of action of environmental toxicants and the genetic determinants of the susceptibility to toxicant-induced injury
Recommended by Scientific/Professional Society or General Public No
2. Kyle Steenland
2. Kyle Steenland
Academic and Professional Credentials PhD
Current Position Title Professor
Organizational Affiliation(s) Professor, Department of Environmental Health
Professor, Department of Epidemiology
Rollins School of Public Health
Emory University
Areas of Expertise, Discipline, Relevant Experiences Statistical modeling, environmental health, epidemiology, pesticides in relation to neurodegenerative diseases, adult lead exposure and cancer, PFOA and a variety of diseases
Recommended by Scientific/Professional Society or General Public No
3. Lewis Weinstock
3. Lewis Weinstock
Academic and Professional Credentials
Current Position Title Group Lead, Ambient Aire Monitor Group
Organizational Affiliation(s) Office of Air Quality Planning & Standards
U.S. Environmental Protection Agency
Areas of Expertise, Discipline, Relevant Experiences EPA expert on EPA national ambient air monitoring networks for multiple pollutants; particular expertise on ethylene oxide air levels. Eight publications from 2005-2019, cited by 428 other papers.
Expertise crucial for review of 5.3.1 Potential for Human Exposure: Releases to The Environment: Air (air monitoring measurements & methods) to ensure that information is complete and accurate
Recommended by Scientific/Professional Society or General Public No
4. Thomas E. McKone
4. Thomas E. McKone
Academic and Professional Credentials PhD
Current Position Title Professor Emeritus
Organizational Affiliation(s) Environmental Health Sciences,
Lawrence Berkeley National Laboratory,
UC Berkeley School of Public Health
Areas of Expertise, Discipline, Relevant Experiences Risk assessment; Model uncertainty and reliability in exposure/risk assessment; Environmental and occupational radioactivity; Mass transfer at environmental and human/environment boundaries
Recommended by Scientific/Professional Society or General Public No
5. Timothy R. Fennell
5. Timothy R. Fennell
Academic and Professional Credentials PhD
Current Position Title Director, Analytical Chemistry & Pharmaceutics
Organizational Affiliation(s) RTI International
Research Triangle Park
North Caroline, USA
Areas of Expertise, Discipline, Relevant Experiences Biomarkers, exposure assessment, pharmacokinetics, nanotoxicology, biochemistry
Recommended by Scientific/Professional Society or General Public No
6. James Wagner
6. James Wagner
Academic and Professional Credentials PhD
Current Position Title Associate Professor
Organizational Affiliation(s) Pathobiology and Diagnostic Investigation
College of Veterinary Medicine;
Michigan State University
Areas of Expertise, Discipline, Relevant Experiences Pathophysiology and pharmacology; toxicology; mechanisms of airway injury and systemic responses induced by inhalation exposures to pathogens, toxicants, and environmental pollutants; role of diet and metabolic susceptibility in adverse cardiopulmonary responses to air pollutant exposure; nanomaterials
Recommended by Scientific/Professional Society or General Public No
Page last reviewed: October 1, 2020