Toxicological Profile for Methyl tert-Butyl Ether (MTBE)

Title: Toxicological Profile for Methyl tert-Butyl Ether (MTBE)

Subject of planned Report: The ATSDR toxicological profile succinctly characterizes the toxicologic and adverse health effects for the substance being described.

Purpose of Planned Report: The purpose of the toxicological profile is to provide a source of toxicological and epidemiological data on hazardous substances to support of public health assessment efforts.

Type of Dissemination: ISI

Timing of Review (including deferrals): August 2020

Type of Review (panel, individual or alternative procedure): Individual

Opportunities for the Public to Comment (how and when): ATSDR made a draft of this profile available for public comment in 2020.

Peer Reviewers Provided with Public Comments before the Review: No

Anticipated Number of Reviewers: 3

Primary Disciplines or Expertise: toxicology, epidemiology, environmental health, and medicine

Reviewers Selected by (agency or designated outside organization): CDC/ATSDR

Public Nominations Requested for Reviewers: No

1. Clifford P Weisel
1. John DeSesso
Academic and Professional Credentials  PhD
Current Position Title Professor
Organizational Affiliation(s) Rutgers University

School of Public Health

Environmental and Population Health Bio-Sciences

Areas of Expertise, Discipline, Relevant Experiences determination of biomarkers of exposure; measurement of multi-route exposures to volatile organic compounds and disinfection by-products in drinking water; exposure to children; the role of air pollution in exacerbation of asthma; exposures within aircraft and other modes of transportation; the sources of pollutants to indoor air and their contribution to personal exposure, and how exposures alter the lung microbiome.
Recommended by Scientific/Professional
Society or General Public
No
2. Deborah A. Slechta
1. John DeSesso
Academic and Professional Credentials PhD
Current Position Title Professor
Organizational Affiliation(s) Environmental Medicine and Pediatrics

University of Rochester Medical Center

School of Medicine and Dentistry

University of Rochester

Areas of Expertise, Discipline, Relevant Experiences environmental medicine; neurotoxicology; teratology; the relationships between brain neurotransmitter systems and children’s neurodevelopment and how such relationships are altered by exposures to environmental toxicants;
Recommended by Scientific/Professional
Society or General Public
No
3. James V. Bruckner
3. Andrew Salmon
Academic and Professional Credentials PhD
Current Position Title Professor Emeritus
Organizational Affiliation(s) Interdisciplinary Toxicology Program

Pharmaceutical & Biomedical Sciences, College of Pharmacy

University of Georgia

Areas of Expertise, Discipline, Relevant Experiences Toxicology; PBPK modeling of VOCs; pesticide toxicology
Recommended by Scientific/Professional
Society or General Public
No

Additional elements to be added to the public posting as they become available:

Charge to Peer Reviewers

CDC/ATSDR’s Response to Reviewers’ Comments: Response to Methyl tert-Butyl Ether (MTBE) pdf icon[PDF – 480 KB]

The ISI/HISA Dissemination Itself

Page last reviewed: March 14, 2022